Newsbites features short notes about industry news and views as well as news from Care and Thornton & Ross.


Turbo-charging a decongestant

22 Jun 2015

In a recent European trial, it was shown that Care Allergy Defence (methylcellulose powder) used in conjunction with a locally applied decongestant (nasal oxymetazoline) enhanced the decongestant effect in patients with allergic rhinitis.

The background to the trial was the proposition that prolonging the contact time of a drug with the tissues inside the nose would improve its efficacy – methylcellulose has an adhesive capability. The gel layer formed by the methylcellulose powder might also delay the clearance of the oxymetazoline.

A double blind, placebo controlled study was conducted in 40 patients with one group receiving one puff of oxymetazoline followed by one puff of methylcellulose and the other group receiving one puff of oxymetazoline followed by one puff of placebo (lactose powder) for 8 days. Peak Inspiratory Nasal Flow was measured on each day. Regular treatment was then discontinued (rescue medication only) and measurements taken again on day 15.

The results showed that not only did Care Allergy Defence enhance the decongestant effect of oxymetazoline but that the effect was carried over for another week after discontinuation of treatment.

Care Allergy Defence is steroid and antihistamine-free, making it a great choice for pregnant and breast feeding women as well as children who need allergy relief.

To view a poster showing details of the trial click HERE

General Enquiries

Preferred method of contact:   Email Phone

Your contact details will be used only as a form of contact between you and Thornton & Ross Ltd. We do not forward or sell your information to any third party.

Contact Details

Thornton & Ross Limited
Linthwaite Labs,
Linthwaite, Huddersfield,

Telephone -+ 44 (0) 1484 842 217
Fax - +44 (0) 1484 847 301

Press Information

Please contact the Care press office at:

Pegasus PR -

Care Sitemap

Care Medicines
A source for information on new developments, providing pharmacy staff with insights & seasonal suggestions for merchandising as well as a ‘Forum’ for issues facing pharmacy in the 21st century.

Search our product range. In-depth information available to help you make the right recommendation.

Keep up-to-date with Newsbites from the pharmacy world.

Understand your customers, informed merchandising decisions and intelligent use of POS materials

Useful Information
Professional Resource, Product Developments, Brochure Downloads & your Care Sales Rep contact details.

General Enquiries
For anything else we have missed.